Saccharomyces cerevisiae (S288c)

PFY1

CLS5, PRF1, profilin, L000001407, YOR122C
Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS
Download Curated Data for this Protein
34517
559292
Switch View:
  • Interactors 747
  • Interactions 1,000
  • Network
  • PTM Sites 3