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Saccharomyces cerevisiae (S288c)

SLM1

LIT2, YIL105C

Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex; protein abundance increases in response to DNA replication stress; SLM1 has a paralog, SLM2, that arose from the whole genome duplication

GO Process (7)

GO Function (2)

GO Component (6)

Gene Ontology Biological Process

TOR signaling [IPI]

actin cytoskeleton organization [IGI]

actin filament bundle assembly [IGI]

eisosome assembly [IGI]

endosomal transport [IGI]

establishment or maintenance of actin cytoskeleton polarity [IPI]

regulation of cell growth [IGI, IPI]

Gene Ontology Molecular Function

phosphatidylinositol-4,5-bisphosphate binding [IDA]
sphingolipid binding [IDA]

Gene Ontology Cellular Component

TORC2 complex [IPI]

cytoplasm [IDA]

membrane raft [IDA]

mitochondrion [IDA]

plasma membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34886

559292

Interactors 184
Interactions 265
Network
PTM Sites 18