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Saccharomyces cerevisiae (S288c)

ICE2

YIL090W

Integral ER membrane protein with type-III transmembrane domains; required for maintenance of ER zinc homeostasis; necessary for efficient targeting of Trm1p tRNA methyltransferase to inner nuclear membrane; mutations cause defects in cortical ER morphology in both the mother and daughter cells

GO Process (4)

GO Function (0)

GO Component (5)

Gene Ontology Biological Process

cellular zinc ion homeostasis [IMP]

endoplasmic reticulum inheritance [IGI, IMP]

protein targeting to nuclear inner membrane [IMP]

septin ring assembly [IGI, IMP]

Gene Ontology Cellular Component

cortical endoplasmic reticulum [IDA]

endoplasmic reticulum [IDA]

integral component of endoplasmic reticulum membrane [IDA]

integral component of membrane [ISM]

perinuclear endoplasmic reticulum [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34902

559292

Interactors 683
Interactions 1,208
Network
PTM Sites 1