Saccharomyces cerevisiae (S288c)
SDS3
L000003384, YIL084C
Component of the Rpd3L histone deacetylase complex; required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; relocalizes to the cytosol in response to hypoxia; cells defective in SDS3 display pleiotropic phenotypes
GO Process (9)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- cell adhesion involved in single-species biofilm formation [IMP]
- chromatin silencing [IGI, IMP]
- histone deacetylation [IMP, IPI]
- negative regulation of chromatin silencing at rDNA [IMP]
- negative regulation of chromatin silencing at silent mating-type cassette [IMP]
- negative regulation of chromatin silencing at telomere [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to heat stress [IMP]
- regulation of invasive growth in response to glucose limitation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
34908
559292
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- Interactors 812
- Interactions 1,383
- Network
- PTM Sites 10