Saccharomyces cerevisiae (S288c)

HOP1

L000000802, YIL072W

Meiosis-specific protein required for chromosome synapsis; displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for chiasma formation; in vitro, displays the ability to promote intra- and intermolecular synapsis between double-stranded DNA molecules and to fold DNA into rigid protein-DNA filaments

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

meiotic recombination checkpoint [IGI]

synapsis [IMP]

synaptonemal complex assembly [IMP]

Gene Ontology Molecular Function

four-way junction DNA binding [IDA]

Gene Ontology Cellular Component

condensed nuclear chromosome [IDA]

lateral element [IPI]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34920

559292

PTM statistics

Proteins

PTM Sites

Publications

Phosphorylation Sites (8)

Interactors 76
Interactions 127
Network
PTM Sites 8

Sites with Multi-PTMs

Displaying 1 protein with 8 total post translational modifications

Sort By: [Default] [Alphabetical] [PTM count] [Length] [Status]

View

NP_012193

Hop1p

Length: 605

1
MSNKQLVKPK TETKTEITTE QSQKLLQTML TMSFGCLAFL RGLFPDDIFV
51
DQRFVPEKVE KNYNKQNTSQ NNSIKIKTLI RGKSAQADLL LDWLEKGVFK
101
SIRLKCLKAL SLGIFLEDPT DLLENYIFSF DYDEENNVNI NVNLSGNKKG
151
SKNADPENET ISLLDSRRMV QQLMRRFIII TQSLEPLPQK KFLTMRLMFN
201
DNVDEDYQPE LFKDATFDKR ATLKVPTNLD NDAIDVGTLN TKHHKVALSV
251
LSAATSSMEK AGNTNFIRVD PFDLILQQQE ENKLEESVPT KPQNFVTSQT
301
TNVLGNLLNS SQASIQPTQF VSNNPVTGIC SCECGLEVPK AATVLKTCKS
351
CRKTLHGICY GNFLHSSIEK CFTCIFGPSL DTKWSKFQDL MMIRKVFRFL
401
VRKKKGFPAS ITELIDSFIN VEDQNNEVKE RVAFALFVFF LDETLCLDNG
451
GKPSQTIRYV TSSVLVDVKG IVIPNTRKQL NVNHEYKWHF TTSSPKAESF
501
YQEVLPNSRK QVESWLQDIT NLRKVYSEAL SPSSTLQELD LNSSLPTQDP
551
IISGQKRRRY DLDEYLEEDK SSVVNDTIKA KDFDESVPAK IRKISVSKKT
601
LKSNW

Location	PTM	Residue	Source(s)	Note(s)
22	Phosphorylation	S	Carballo JA (2008)	eyJSRUxBVElPTlNISVBTIjp7Ik1FQzEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyODM2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL21lYzEuaHRtbCcgYWx0PSdNRUMxJz5NRUMxPFwvYT48XC9zcGFuPiAoS2luYXNlKSIsIlRFTDEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyNjE2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3RlbDEuaHRtbCcgYWx0PSdURUwxJz5URUwxPFwvYT48XC9zcGFuPiAoS2luYXNlKSJ9fQ==
69	Phosphorylation	S	Carballo JA (2008)	eyJSRUxBVElPTlNISVBTIjp7Ik1FQzEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyODM2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL21lYzEuaHRtbCcgYWx0PSdNRUMxJz5NRUMxPFwvYT48XC9zcGFuPiAoS2luYXNlKSIsIlRFTDEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyNjE2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3RlbDEuaHRtbCcgYWx0PSdURUwxJz5URUwxPFwvYT48XC9zcGFuPiAoS2luYXNlKSJ9fQ==
181	Phosphorylation	T	Carballo JA (2008)	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
298	Phosphorylation	S	Carballo JA (2008)	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
311	Phosphorylation	S	Carballo JA (2008)	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
318	Phosphorylation	T	Carballo JA (2008)	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
454	Phosphorylation	S	Carballo JA (2008)	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
547	Phosphorylation	T	Carballo JA (2008)	eyJSRUxBVElPTlNISVBTIjp7Ik1FQzEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyODM2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL21lYzEuaHRtbCcgYWx0PSdNRUMxJz5NRUMxPFwvYT48XC9zcGFuPiAoS2luYXNlKSIsIlRFTDEiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMyNjE2XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3RlbDEuaHRtbCcgYWx0PSdURUwxJz5URUwxPFwvYT48XC9zcGFuPiAoS2luYXNlKSJ9fQ==

Relationships

Protein	Relationship	Location	PTM	Residue	Identity	Source(s)
MEC1	Kinase	22	Phosphorylation	S	catalytic	Carballo JA (2008)
TEL1	Kinase	22	Phosphorylation	S	catalytic	Carballo JA (2008)
MEC1	Kinase	69	Phosphorylation	S	catalytic	Carballo JA (2008)
TEL1	Kinase	69	Phosphorylation	S	catalytic	Carballo JA (2008)
MEC1	Kinase	181	Phosphorylation	T	catalytic	Carballo JA (2008)
TEL1	Kinase	181	Phosphorylation	T	catalytic	Carballo JA (2008)
MEC1	Kinase	298	Phosphorylation	S	catalytic	Carballo JA (2008)
TEL1	Kinase	298	Phosphorylation	S	catalytic	Carballo JA (2008)
MEC1	Kinase	311	Phosphorylation	S	catalytic	Carballo JA (2008)
TEL1	Kinase	311	Phosphorylation	S	catalytic	Carballo JA (2008)
MEC1	Kinase	318	Phosphorylation	T	catalytic	Carballo JA (2008)
TEL1	Kinase	318	Phosphorylation	T	catalytic	Carballo JA (2008)
MEC1	Kinase	454	Phosphorylation	S	catalytic	Carballo JA (2008)
TEL1	Kinase	454	Phosphorylation	S	catalytic	Carballo JA (2008)
MEC1	Kinase	547	Phosphorylation	T	catalytic	Carballo JA (2008)
TEL1	Kinase	547	Phosphorylation	T	catalytic	Carballo JA (2008)

Result Summary