Saccharomyces cerevisiae (S288c)


L000004013, YML130C
Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining proper redox balance in ER; feedback regulation of Ero1p occurs via reduction and oxidation of Ero1p regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds
GO Process (2)
GO Function (2)
GO Component (1)

Gene Ontology Cellular Component

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 344 Published Interactions For This Protein
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  • Interactors (286)
  • Interactions (344)
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  • PTM Sites (1)