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Saccharomyces cerevisiae (S288c)

ORC1

origin recognition complex subunit 1, L000003162, YML065W

Largest subunit of the origin recognition complex; involved in directing DNA replication by binding to replication origins; also involved in transcriptional silencing; exhibits ATPase activity; ORC1 has a paralog, SIR3, that arose from the whole genome duplication

GO Process (3)

GO Function (4)

GO Component (4)

Gene Ontology Biological Process

DNA replication initiation [IMP]

chromatin silencing at silent mating-type cassette [IDA, IGI]

pre-replicative complex assembly involved in nuclear cell cycle DNA replication [IDA, IMP]

Gene Ontology Molecular Function

ATP binding [IDA, IMP]
ATPase activity [IMP]
DNA replication origin binding [IDA]
chromatin binding [IDA]

Gene Ontology Cellular Component

DNA replication preinitiation complex [IDA]

nuclear origin of replication recognition complex [IDA, IMP]

nuclear pre-replicative complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35101

559292

Interactors 672
Interactions 891
Network
PTM Sites 3