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Saccharomyces cerevisiae (S288c)

YOX1

L000002540, YML027W

Homeobox transcriptional repressor; binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOX1 has a paralog, YHP1, that arose from the whole genome duplication

GO Process (1)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

negative regulation of transcription involved in G1/S transition of mitotic cell cycle [IGI, IMP]

Gene Ontology Molecular Function

RNA polymerase II regulatory region sequence-specific DNA binding [IDA, IMP]
RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IMP, IPI]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

nuclear chromatin [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35142

559292

Interactors 88
Interactions 111
Network
PTM Sites 4