Saccharomyces cerevisiae (S288c)


KTI1, S000028426, YML014W
tRNA methyltransferase; catalyzes modification of wobble bases in tRNA anticodons to 2, 5-methoxycarbonylmethyluridine and 5-methoxycarbonylmethyl-2-thiouridine; may act as part of a complex with Trm112p; deletion mutation increases translational infidelity, including amino acid misincorporation and -1 frameshifting, and also confers resistance to zymocin; null mutant displays activation of stress responses
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  • Interactors 116
  • Interactions 143
  • Network
  • PTM Sites 2