Saccharomyces cerevisiae (S288c)

IOC4

YMR044W
Member of a complex (Isw1b) with Isw1p and Ioc2p; interacts directly with H3K36me3 nucleosomes through its PWWP domain to recruit the Isw1b complex to open reading frames in a Set2p-dependent manner; Isw1b exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing
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  • Interactors 204
  • Interactions 278
  • Network
  • PTM Sites 5