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Saccharomyces cerevisiae (S288c)

YKU80

HDF2, L000004089, YMR106C

Subunit of the telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein via interaction with the TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair

GO Process (6)

GO Function (4)

GO Component (3)

Gene Ontology Biological Process

chromatin assembly or disassembly [IDA]

chromatin silencing [IDA, IMP]

donor selection [IDA, IGI, IMP]

double-strand break repair via homologous recombination [IMP]

protein localization to chromosome [IGI]

telomere maintenance [IMP]

Gene Ontology Molecular Function

DNA binding [IDA]
RNA binding [IDA]
damaged DNA binding [TAS]
telomeric DNA binding [IDA]

Gene Ontology Cellular Component

Ku70:Ku80 complex [IDA]

nuclear chromatin [TAS]

nuclear telomeric heterochromatin [TAS]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35281

559292

Interactors 308
Interactions 437
Network
PTM Sites 2