Saccharomyces cerevisiae (S288c)

GUA1

GMP synthase (glutamine-hydrolyzing), L000000744, YMR217W
GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA
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  • Interactors 53
  • Interactions 57
  • Network
  • PTM Sites 6