Saccharomyces cerevisiae (S288c)


OSR1, Zn(2+) transporter ZRC1, L000002570, YMR243C
Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication
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  • Interactors 185
  • Interactions 229
  • Network
  • PTM Sites 13