BioGRID COVID-19 Coronavirus Curation Project
Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions

Saccharomyces cerevisiae (S288c)

CUE1

KIS4, L000003518, YMR264W

Ubiquitin-binding protein; endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination; CUE1 has a paralog, CUE4, that arose from the whole genome duplication

GO Process (2)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

ER-associated ubiquitin-dependent protein catabolic process [IMP]

establishment of protein localization to endoplasmic reticulum membrane [IMP]

Gene Ontology Molecular Function

ubiquitin binding [IDA]
ubiquitin-protein transferase activator activity [IDA]

Gene Ontology Cellular Component

Doa10p ubiquitin ligase complex [IDA]

Hrd1p ubiquitin ligase ERAD-L complex [IDA]

integral component of endoplasmic reticulum membrane [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35442

559292

Interactors 192
Interactions 306
Network
PTM Sites 2