Saccharomyces cerevisiae (S288c)

COS1

L000004060, YNL336W

Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins

GO Process (0)

GO Function (0)

GO Component (3)

Gene Ontology Cellular Component

fungal-type vacuole [IDA]

fungal-type vacuole membrane [IDA]

integral component of membrane [ISM]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35505

559292

Interactor Statistics

Proteins/Genes

Publications

Interactors w/ Physical (LTP) Evidence (3)

Interactors 85
Interactions 85
Network
PTM Sites 7

Sites with Multi-PTMs

Displaying 1 protein 1 non-assigned with 7 total post translational modifications

Sort By: [Default] [Alphabetical] [PTM count] [Length] [Status]

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NP_014063

Cos1p

Length: 381

1
MKENELKNEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR
51
IWMLLWLPLS VWWKLSNNCI YPLIVSLLVL FLGPIFVLVI CGLSRKRSLS
101
KQLIQFCKEV TENTPSSDPH DWEVVAANLN SYLYENKAWN TKYFFFNAMV
151
CQEAFRTTLL EPFSLKKDEA AKVKSFKDSV PYIEEALGVY FREVEKQWKL
201
FNSEKSWSPV GLEDAKLPKE AYRFKLTWFL KRISNIFMLI PFLNFLCCIY
251
VSRGMCLLLR TFYLGWILFM LVQGFQNMRM IVLSVKMEHK MQFLSTIINE
301
QESGANGWDE IAKKMNRYLF EKKVWKNEEF FFDGIDCEWF FSHFFYRVLS
351
AKKSMRALSL NVELWPYIKE AQLSCSEESL A

Location	PTM	Residue	Source(s)	Note(s)
7	Ubiquitination	K	Iesmantavicius V (2014)	-
10	Ubiquitination	K	Back S (2019)	-
			Iesmantavicius V (2014)	-
			Swaney DL (2013)	-
18	Ubiquitination	K	Back S (2019)	-
			Beltrao P (2012)	-
			Hitchcock AL (2003)	-
			Iesmantavicius V (2014)	-
			Starita LM (2011)	-
			Swaney DL (2013) [show 1 more ]	-
199	Ubiquitination	K	Back S (2019)	-
199	Ubiquitination	K	Swaney DL (2013)	-
205	Ubiquitination	K	Back S (2019)	-
			Beltrao P (2012)	-
			Hitchcock AL (2003)	-
			Iesmantavicius V (2014)	-
			Kolawa NJ (2013)	-
			Peng J (2003)	-
			Swaney DL (2013) [show 2 more ]	-
216	Ubiquitination	K	Swaney DL (2013)	-

View

Non-Assigned PTMs

Post translational modifications that are currently unassigned to a specific residue location.

Location	PTM	Residue	Source(s)	Note(s)
-	Ubiquitination	K	Hitchcock AL (2003)	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
			Kolawa NJ (2013)	eyJOT1RFUyI6WyJUYWJsZSBTMTsgVmFsaWQgU3Vic3RyYXRlIiwibGlrZWx5IHViaXF1aXRpbiBjb25qdWdhdGUiXSwiUkVMQVRJT05TSElQUyI6eyJVQkMiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzExMzE2NFwvc3VtbWFyeVwvaG9tby1zYXBpZW5zXC91YmMuaHRtbCcgYWx0PSdVQkMnPlVCQzxcL2E+PFwvc3Bhbj4iLCJVQkk0IjoiPHNwYW4+PGEgaHJlZj0naHR0cHM6XC9cL3RoZWJpb2dyaWQub3JnXC8zMTIxNVwvc3VtbWFyeVwvc2FjY2hhcm9teWNlcy1jZXJldmlzaWFlXC91Ymk0Lmh0bWwnIGFsdD0nVUJJNCc+VUJJNDxcL2E+PFwvc3Bhbj4ifX0=
			Peng J (2003)	eyJSRUxBVElPTlNISVBTIjp7IlVCQyI6IjxzcGFuPjxhIGhyZWY9J2h0dHBzOlwvXC90aGViaW9ncmlkLm9yZ1wvMTEzMTY0XC9zdW1tYXJ5XC9ob21vLXNhcGllbnNcL3ViYy5odG1sJyBhbHQ9J1VCQyc+VUJDPFwvYT48XC9zcGFuPiIsIlVCSTQiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMxMjE1XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3ViaTQuaHRtbCcgYWx0PSdVQkk0Jz5VQkk0PFwvYT48XC9zcGFuPiJ9fQ==
			Phillips AH (2013)	eyJSRUxBVElPTlNISVBTIjp7IlVCQyI6IjxzcGFuPjxhIGhyZWY9J2h0dHBzOlwvXC90aGViaW9ncmlkLm9yZ1wvMTEzMTY0XC9zdW1tYXJ5XC9ob21vLXNhcGllbnNcL3ViYy5odG1sJyBhbHQ9J1VCQyc+VUJDPFwvYT48XC9zcGFuPiIsIlVCSTQiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMxMjE1XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3ViaTQuaHRtbCcgYWx0PSdVQkk0Jz5VQkk0PFwvYT48XC9zcGFuPiJ9fQ==
			Starita LM (2011)	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

Relationships

Protein	Relationship	Location	PTM	Residue	Identity	Source(s)
UBI4	Conjugate	-	Ubiquitination	K	PTM	Hitchcock AL (2003)
						Kolawa NJ (2013)
						Peng J (2003)
						Starita LM (2011)
UBC	Conjugate	-	Ubiquitination	K	PTM	Phillips AH (2013)

Result Summary

COS1

Gene Ontology Cellular Component

NP_014063

Non-Assigned PTMs

Relationships