Saccharomyces cerevisiae (S288c)

NRD1

Nrd1 complex RNA-binding subunit, L000002862, YNL251C
RNA-binding subunit of Nrd1 complex; complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; interacts with CTD of RNA pol II large subunit Rpo21p at phosphorylated Ser5 to direct transcription termination of non-polyadenylated transcripts; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; role in regulation of mitochondrial abundance and cell size
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  • Interactors 311
  • Interactions 435
  • Network
  • PTM Sites 5