Saccharomyces cerevisiae (S288c)

SIN4

BEL2, GAL22, MED16, RYE1, SDI3, SSF5, SSN4, SSX3, TSF3, L000001888, S000029516, L000002099, YNL236W

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription

GO Process (3)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

RNA polymerase II transcriptional preinitiation complex assembly [IMP]

negative regulation of transcription from RNA polymerase II promoter [IMP]

positive regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

RNA polymerase II activating transcription factor binding [IDA]

Gene Ontology Cellular Component

core mediator complex [IDA]

mediator complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35603

559292

Interactors 606
Interactions 950
Network
PTM Sites 5

Result Summary

SIN4

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II activating transcription factor binding [IDA]

Gene Ontology Cellular Component