Saccharomyces cerevisiae (S288c)
WHI3
mRNA-binding protein WHI3, L000002486, YNL197C
RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; regulates genes involved in the cell cycle, sister chromatid cohesion, and stress response; acts as a cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start; Tpk1p (PKA) mediated phosphorylation (S568) inhibits Whi3p function, decreasing its interaction with CLN3 mRNA; regulates ploidy
GO Process (6)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- mRNA binding [IDA, IMP]
- mRNA binding [IDA, IMP]
Gene Ontology Cellular Component
Download Curated Data for this Protein
35636
559292
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- Interactors 557
- Interactions 724
- Network
- PTM Sites 7