Saccharomyces cerevisiae (S288c)

APC1

anaphase promoting complex subunit 1, L000004053, YNL172W
Largest subunit of the Anaphase-Promoting Complex/Cyclosome; APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; localizes to nuclear foci that become diffuse upon DNA replication stress
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  • Interactors 506
  • Interactions 592
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  • PTM Sites 6