Saccharomyces cerevisiae (S288c)

THO2

LDB5, RLR1, ZRG13, L000002589, YNL139C

Subunit of the THO complex; THO is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids

GO Process (5)

GO Function (3)

GO Component (4)

Gene Ontology Biological Process

DNA recombination [IMP]

mRNA 3'-end processing [IMP]

mRNA export from nucleus [IMP]

transcription elongation from RNA polymerase II promoter [IMP]

transcription-coupled nucleotide-excision repair [IMP]

Gene Ontology Molecular Function

DNA binding [IPI]
mRNA binding [IDA]
nucleic acid binding [IDA]

Gene Ontology Cellular Component

THO complex part of transcription export complex [IPI]

chromosome, telomeric region [IDA]

nucleoplasmic THO complex [IMP, IPI]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35687

559292

Interactors 100
Interactions 197
Network
PTM Sites 9

Result Summary

THO2

Gene Ontology Biological Process

Gene Ontology Molecular Function

DNA binding [IPI]mRNA binding [IDA]nucleic acid binding [IDA]

Gene Ontology Cellular Component

DNA binding [IPI]
mRNA binding [IDA]
nucleic acid binding [IDA]