Saccharomyces cerevisiae (S288c)
DMA2
CHF2, ubiquitin-conjugating protein DMA2, S000029720, YNL116W
Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- cellular bud neck septin ring organization [IGI]
- establishment of mitotic spindle orientation [IGI]
- mitotic spindle orientation checkpoint [IGI]
- protein autoubiquitination [IDA]
- protein localization to bud neck [IGI]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IGI]
- septin ring assembly [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
35710
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- Interactors 181
- Interactions 234
- Network
- PTM Sites 5