Saccharomyces cerevisiae (S288c)

TOP2

TOR3, TRF3, DNA topoisomerase 2, L000002320, YNL088W
Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation
Download Curated Data for this Protein
35735
559292
Switch View:
  • Interactors 285
  • Interactions 362
  • Network
  • PTM Sites 24