Saccharomyces cerevisiae (S288c)


tropomyosin TPM1, L000002328, YNL079C
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication
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  • Interactors 692
  • Interactions 1,030
  • Network
  • PTM Sites 15