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Saccharomyces cerevisiae (S288c)

TRM112

S000079653, YNR046W

Protein involved in methylation of tRNA, rRNA, and translation factors; also involved in ribosome biogenesis; subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; interacts with and stabilizes 18S rRNA methyltransferase Bud23p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; relative distribution to the nucleus increases upon DNA replication stress

GO Process (7)

GO Function (3)

GO Component (5)

Gene Ontology Biological Process

maturation of LSU-rRNA [IMP]

maturation of SSU-rRNA [IMP]

peptidyl-glutamine methylation [IDA]

rRNA (guanine-N7)-methylation [IMP]

ribosomal large subunit biogenesis [IMP]

ribosomal small subunit biogenesis [IMP]

tRNA methylation [IMP]

Gene Ontology Molecular Function

protein methyltransferase activity [IDA]
rRNA (guanine) methyltransferase activity [IMP]
tRNA (guanine-N2-)-methyltransferase activity [IDA, IMP]

Gene Ontology Cellular Component

cytoplasm [IDA]

eRF1 methyltransferase complex [IPI]

nucleolus [IDA]

tRNA (m2G10) methyltransferase complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35871

559292

Interactors 88
Interactions 130
Network
PTM Sites 3