Saccharomyces cerevisiae (S288c)

AFT2

YPL202C

Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication

GO Process (4)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

cellular iron ion homeostasis [IGI]

cellular response to oxidative stress [IGI]

positive regulation of transcription from RNA polymerase II promoter [IDA]

positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation [IGI]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

mitochondrion [IDA]

nucleus [IC]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35982

559292

Interactors 67
Interactions 86
Network

Result Summary

AFT2

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
sequence-specific DNA binding [IDA]