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Saccharomyces cerevisiae (S288c)

KES1

BSR3, LPI3, OSH4, oxysterol-binding protein KES1, L000000894, YPL145C

One of seven members of the yeast oxysterol binding protein family; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; KES1 has a paralog, HES1, that arose from the whole genome duplication

GO Process (8)

GO Function (6)

GO Component (3)

Gene Ontology Biological Process

ER to Golgi ceramide transport [IMP]

endocytosis [IGI]

exocytosis [IGI]

maintenance of cell polarity [IGI]

positive regulation of phosphatase activity [IDA]

post-Golgi vesicle-mediated transport [IGI]

sphingolipid metabolic process [IMP]

sterol transport [IDA, IGI, IMP]

Gene Ontology Molecular Function

lipid binding [IDA, IMP]
oxysterol binding [IMP, IPI, ISS]
phosphatidic acid binding [IDA]
phosphatidylinositol-4,5-bisphosphate binding [IMP, IPI]
phosphatidylinositol-4-phosphate binding [IDA]
sterol transporter activity [IDA, IMP]

Gene Ontology Cellular Component

Golgi membrane [IDA]

cytoplasm [IDA]

extrinsic component of membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36038

559292

Interactors 306
Interactions 413
Network
PTM Sites 14