Saccharomyces cerevisiae (S288c)

KAR3

OSR11, L000000888, YPR141C

Minus-end-directed microtubule motor; functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate

GO Process (6)

GO Function (3)

GO Component (6)

Gene Ontology Biological Process

karyogamy involved in conjugation with cellular fusion [IMP]

meiotic nuclear division [IDA, IMP]

mitotic nuclear division [IGI]

mitotic sister chromatid cohesion [IGI, IMP]

nuclear migration involved in conjugation with cellular fusion [IMP]

regulation of mitotic spindle organization [IMP]

Gene Ontology Molecular Function

microtubule binding [IDA]
minus-end-directed microtubule motor activity [IDA]
protein heterodimerization activity [IPI]

Gene Ontology Cellular Component

cytoplasmic microtubule [IDA]

integral component of membrane [ISM]

microtubule [IDA]

nucleus [IDA]

spindle pole [IDA]

spindle pole body [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36310

559292

Interactors 641
Interactions 1,205
Network
PTM Sites 7

Result Summary

KAR3

Gene Ontology Biological Process

Gene Ontology Molecular Function

microtubule binding [IDA]minus-end-directed microtubule motor activity [IDA]protein heterodimerization activity [IPI]

Gene Ontology Cellular Component

microtubule binding [IDA]
minus-end-directed microtubule motor activity [IDA]
protein heterodimerization activity [IPI]