Saccharomyces cerevisiae (S288c)

AOS1

RHC31, E1 ubiquitin-activating protein AOS1, L000004031, YPR180W
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia
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  • Interactors 224
  • Interactions 244
  • Network
  • PTM Sites 3