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Saccharomyces cerevisiae (S288c)

GIC1

L000003313, YHR061C

Protein involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain; relocalizes from bud neck to nucleus upon DNA replication stress; GIC1 has a paralog, GIC2, that arose from the whole genome duplication

GO Process (5)

GO Function (2)

GO Component (7)

Gene Ontology Biological Process

Rho protein signal transduction [TAS]

axial cellular bud site selection [TAS]

establishment of cell polarity [IGI]

regulation of exit from mitosis [IMP]

septin ring organization [IGI, IPI]

Gene Ontology Molecular Function

Rho GTPase activator activity [IDA, IGI, IPI]
Rho GTPase binding [IPI]

Gene Ontology Cellular Component

actin cap [TAS]

cellular bud neck [IDA]

cellular bud tip [IDA]

cytoplasm [IDA]

incipient cellular bud site [IDA]

mating projection tip [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36493

559292

Interactors 128
Interactions 184
Network