Saccharomyces cerevisiae (S288c)

UBA4

YHR1, YHR111W

E1-like protein that activates Urm1p before urmylation; also acts in thiolation of the wobble base of cytoplasmic tRNAs by adenylating and then thiolating Urm1p; receives sulfur from Tum1p

GO Process (7)

GO Function (4)

GO Component (1)

Gene Ontology Biological Process

cell budding [IGI]

cellular response to oxidative stress [IMP]

invasive growth in response to glucose limitation [IGI, IMP]

protein urmylation [IDA, IMP]

regulation of pseudohyphal growth [IMP]

tRNA thio-modification [IMP]

tRNA wobble position uridine thiolation [IMP]

Gene Ontology Molecular Function

URM1 activating enzyme activity [IDA, IMP]
protein adenylyltransferase activity [IMP]
sulfurtransferase activity [IDA, IMP]
thiosulfate sulfurtransferase activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36544

559292

Interactors 357
Interactions 556
Network
PTM Sites 1

Result Summary

UBA4

Gene Ontology Biological Process

Gene Ontology Molecular Function

URM1 activating enzyme activity [IDA, IMP]protein adenylyltransferase activity [IMP]sulfurtransferase activity [IDA, IMP]thiosulfate sulfurtransferase activity [IDA]

Gene Ontology Cellular Component

URM1 activating enzyme activity [IDA, IMP]
protein adenylyltransferase activity [IMP]
sulfurtransferase activity [IDA, IMP]
thiosulfate sulfurtransferase activity [IDA]