Saccharomyces cerevisiae (S288c)

RTT107

ESC4, L000004424, YHR154W
Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress
Download Curated Data for this Protein
36588
559292
Switch View:
  • Interactors 429
  • Interactions 749
  • Network
  • PTM Sites 23