Saccharomyces cerevisiae (S288c)


APG11, APG7, CVT2, L000004701, S000029035, L000004786, YHR171W
Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner
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  • Interactors 126
  • Interactions 193
  • Network