Saccharomyces cerevisiae (S288c)

SKN7

BRY1, POS9, kinase-regulated stress-responsive transcription factor SKN7, L000001908, YHR206W
Nuclear response regulator and transcription factor; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation; relocalizes to the cytosol in response to hypoxia; SKN7 has a paralog, HMS2, that arose from the whole genome duplication
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  • Interactors 273
  • Interactions 441
  • Network
  • PTM Sites 5