Saccharomyces cerevisiae (S288c)


NSE2, PSO10, SUMO ligase MMS21, L000001125, YEL019C
SUMO ligase and component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; required for efficient sister chromatid cohesion; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination; SUMOylates and inhibits Snf1p function
GO Process (1)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Cellular Component

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 505 Published Interactions For This Protein
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  • Interactors (380)
  • Interactions (505)
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  • PTM Sites (1)