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Saccharomyces cerevisiae (S288c)

PRP22

DEAH-box ATP-dependent RNA helicase PRP22, L000001508, YER013W

DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase; associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes; required for proofreading the exon ligation reaction

GO Process (2)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

generation of catalytic spliceosome for second transesterification step [IDA, IMP]

spliceosomal complex disassembly [IMP]

Gene Ontology Molecular Function

ATP-dependent RNA helicase activity [IDA]
second spliceosomal transesterification activity [IDA, IMP]

Gene Ontology Cellular Component

U2-type catalytic step 2 spliceosome [IMP]

U2-type post-spliceosomal complex [IMP]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36745

559292

Interactors 349
Interactions 499
Network
PTM Sites 2