Saccharomyces cerevisiae (S288c)


inositol phosphosphingolipid phospholipase, YER019W
Inositol phosphosphingolipid phospholipase C; mitochondrial membrane localized; hydrolyzes complex sphingolipids to produce ceramide; activates genes required for non-fermentable carbon source metabolism during the diauxic shift; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance
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  • Interactors 255
  • Interactions 331
  • Network
  • PTM Sites 2