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Saccharomyces cerevisiae (S288c)

SRB4

MED17, L000002051, YER022W

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination

GO Process (2)

GO Function (3)

GO Component (1)

Gene Ontology Biological Process

positive regulation of transcription from RNA polymerase II promoter [IDA]

transcription initiation from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

activating transcription factor binding [IDA]
core RNA polymerase II recruiting transcription factor activity [IMP, IPI]
structural molecule activity [IMP]

Gene Ontology Cellular Component

core mediator complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36756

559292

Interactors 192
Interactions 480
Network
PTM Sites 5