Saccharomyces cerevisiae (S288c)

MOT2

NOT4, SIG1, CCR4-NOT core ubiquitin-protein ligase subunit MOT2, L000001887, L000001137, YER068W
Ubiquitin-protein ligase subunit of the CCR4-NOT complex; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p; CCR4-NOT has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication
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  • Interactors 217
  • Interactions 385
  • Network
  • PTM Sites 24