Saccharomyces cerevisiae (S288c)

ARG5,6

bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase, L000000110, YER069W
Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase; N-acetyl-L-glutamate kinase (NAGK) catalyzes the 2nd and N-acetyl-gamma-glutamyl-phosphate reductase (NAGSA), the 3rd step in arginine biosynthesis; synthesized as a precursor which is processed in the mitochondrion to yield mature NAGK and NAGSA; enzymes form a metabolon complex with Arg2p; NAGK C-terminal domain stabilizes the enzymes, slows catalysis and is involved in feed-back inhibition by arginine
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  • Interactors 37
  • Interactions 40
  • Network
  • PTM Sites 2