Saccharomyces cerevisiae (S288c)

DOT6

PBF2, L000004393, YER088C
Protein involved in rRNA and ribosome biogenesis; activated in stochastic pulses of nuclear localization; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; relative distribution to the nucleus increases upon DNA replication stress
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  • Interactors 122
  • Interactions 142
  • Network
  • PTM Sites 47