Saccharomyces cerevisiae (S288c)

MHF2

YDL160C-A
Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM to stabilize and remodel blocked replication forks and repair damaged DNA; mhf2 srs2 double mutants are MMS hypersensitive; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-X, also known as MHF2
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36973
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  • Interactors 32
  • Interactions 46
  • Network
  • PTM Sites 2