Caenorhabditis elegans
COQ-1
CELE_C24A11.9, tag-134, C24A11.9
coq-1 encodes a putative hexaprenyl pyrophosphate synthetase, orthologous to S. cerevisiae COQ1; COQ-1 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-1 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-1(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-1 mutants are not rescued by dietary coenzyme Q.
GO Process (5)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
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- Interactors 5
- Interactions 5
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