Caenorhabditis elegans
GOA-1
CELE_C26C6.2, C26C6.2
goa-1 encodes an ortholog of the heterotrimeric G protein alpha subunit Go (Go/Gi class); GOA-1 activity is required for regulation of a number of behaviors, including locomotion, egg-laying, male mating, and olfactory-mediated behaviors; GOA-1 activity is also required for asymmetric cell division in the early embryo; goa-1 genetically interacts with the egl-30 pathway, and is expressed in all neurons and sex-specific muscles; GOA-1 physically interacts with RIC-8 and AGS-3, and its activity is modulated by RIC-8 and RGS-7 in in vitro assays.
GO Process (17)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [IBA]
- dopamine receptor signaling pathway [IMP]
- embryo development ending in birth or egg hatching [IMP]
- hermaphrodite genitalia development [IMP]
- locomotion [IMP]
- mitotic nuclear division [IMP]
- mitotic spindle organization [IMP]
- negative regulation of locomotion [IMP]
- nematode larval development [IMP]
- oviposition [IMP]
- regulation of feeding behavior [IMP]
- regulation of locomotion [IMP]
- regulation of oviposition [IMP]
- regulation of pharyngeal pumping [IGI]
- reproduction [IMP]
- response to food [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
37947
6239
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- Interactors 34
- Interactions 72
- Network