Caenorhabditis elegans
PAS-4
CELE_C36B1.4, C36B1.4
pas-4 encodes a proteasome alpha-type seven subunit of the core 20S proteasome subcomplex; loss of pas-4 activity via RNAi results in a wide variety of defects including embryonic and larval lethality, sterility, abnormal locomotion, slow growth, and abnormal transgene expression and subcellular localization; loss of pas-4 activity also results in activation of SKN-1, a transcription factor required in adult worms for the acute response to oxidative stress and maternally for embryonic development.
GO Process (4)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
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- Interactors 91
- Interactions 117
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