CELE_C03C11.2, C03C11.2

fog-3 encodes a protein that has similarity, in its N-terminus, to the vertebrate Tob, BTG1, and BTG2 proteins that function in growth control and/or differentiation; in C. elegans, FOG-3 activity is required in the germ line throughout development for initiation and maintenance of spermatogenesis; fog-3 mRNA is expressed at highest levels in the L3, L4, and young adult stages of development, when spermatogenesis occurs; fog-3 transcription appears to be under the control of TRA-1A, which interacts with predicted TRA-1A binding sites in the fog-3 promoter in vitro.

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