Caenorhabditis elegans
LRK-1
CELE_T27C10.6, T27C10.6
lrk-1 encodes the sole C. elegans homolog of the leucine-rich repeat kinases, LRRK1 and the familial Parkinsonism gene PARK8/LRRK2; in C. elegans, lrk-1 is required for polarized localization of synaptic vesicle proteins to presynaptic regions; LRK-1 functions antagonistically to PINK-1 to regulate oxidative and endoplasmic reticulum stress response as well as neurite outgrowth; LRK-1 is widely expressed and localizes to the Golgi apparatus.
GO Process (5)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Download Curated Data for this Protein
38404
6239
Switch View:
- Interactors 2
- Interactions 3
- Network