CELE_H20J04.8, tag-247, sap-1, H20J04.8

mog-2 encodes a U2 snRNP protein that functions as a component of a ubiquitous machinery used for the sperm/oocyte switch during hermaphrodite germline development; mog-2 is defined by a single mutation that results in masculinization of the germ line at 25 degrees C, and maternal-effect embryonic and larval lethality at 15 degrees C; genetic epistasis tests indicate that mog-2, like other mog loci, is required for 3'-UTR-mediated repression of the sex determining gene fem-3; in addition, temperature-shift experiments indicate that mog-2 activity is required during the L4 larval stage and into adulthood for normal germline development and throughout adult life for oogenesis; mog-2 not only affects the sperm/oocyte switch in the germ line, but also functions in somatic tissues.

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