CELE_F10E7.8, F10E7.8

F10E7.8 encodes a FAR11-like protein that inhibits DHC-1 in vivo; F10E7.8 is orthologous to human FAM40A and FAM40B, and to budding yeast FAR11; F10E7.8(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F10E7.8 negatively regulates dynein; in early embryos, F10E7.8 is a pronuclear and nuclear protein; F10E7.8 has no obvious function in mass RNAi assays.

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