Caenorhabditis elegans
CKI-1
CELE_T05A6.1, T05A6.1
cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
GO Process (16)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- body morphogenesis [IMP]
- cell cycle [IMP]
- cell division [IMP]
- embryo development [IMP]
- embryo development ending in birth or egg hatching [IMP]
- germline cell cycle switching, mitotic to meiotic cell cycle [IMP]
- gonad development [IMP]
- hermaphrodite genitalia development [IMP]
- locomotion [IMP]
- mitotic cell cycle arrest [IGI, IMP]
- molting cycle, collagen and cuticulin-based cuticle [IMP]
- nematode larval development [IMP]
- oviposition [IMP]
- regulation of cell proliferation [IMP]
- regulation of meiosis [IMP]
- reproduction [IMP]
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- Interactors 7
- Interactions 9
- Network