Caenorhabditis elegans


CELE_T05H10.2, CeAPN1, T05H10.2
apn-1 encodes a member of the AP (apurinic or apyrimidinic) endonuclease (endo IV) family of DNA repair enzymes; apn-1 activity is essential for DNA repair and maintaining genome integrity; APN-1 exhibits DNA repair activities including nucleotide incision and 3'- to 5' exonuclease activity; expression of an apn-1 cDNA can complement an apn1apn2tpp1 triply mutant S. cerevisiae strain deficient in DNA repair.
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